Combination of bottom up 2D-LC-MS and semi-top-down GelFree-LC-MS enhances coverage of proteome and low molecular weight short open reading frame encoded peptides of the archaeon Methanosarcina mazei.
Cassidy L , Prasse D, Linke D, Schmitz R A, Tholey A (2016); J Proteome Res. doi:10.1021/acs.jproteome.6b00569