Doublesex and mab-3 related transcription factor 1 (DMRT1) is a sex-specific genetic determinant of childhood-onset asthma and is expressed in testis and macrophages.
Schieck M, Schouten J P, Michel S, Suttner K, Toncheva A, Gaertner V D, Illig T, Lipinski S, Franke A, Klintschar M, Kalayci O, Sahiner U M, Birben E, Melén E, Pershagen G, Freidin M B, Ogorodova L M, Granell R, Henderson J, Brunekreef B, Smit H A, Vogelberg C, von Berg A, Bufe A, Heinzmann A, Laub O, Rietschel E, Simma B, Genuneit J, Jonigk D, Postma D S, Koppelman G H, Vonk J M, Timens W, Boezen H M, Kabesch M (2016); J. Allergy Clin. Immunol., doi: 10.1016/j.jaci.2015.12.1305