NK-lysin and its shortened analog NK-2 exhibit potent activities against Trypanosoma cruzi.

Jacobs T, Bruhn H, Gaworski I, Fleischer B, Leippe M (2003); Antimicrob Agents Chemother., 47(2):607-13. PMCID: PMC151766

Identification of diacylated ureas as a novel family of fungus-specific leukocyte-activating pathogen-associated molecules. Amoebapores, archaic effector peptides of protozoan origin, are discharged into phagosomes and kill bacteria by permeabilizing their membranes.