Thioredoxin targets fundamental processes in a methane-producing
 archaeon, Methanocaldococcus jannaschii.

Susanti D, Wong J H, Vensel W H, Loganathan U, DeSantis R, Schmitz R A, Balsera M, Buchanan B B, Mukhopadhyay B (2014); Proc Natl Acad Sci USA, 111(7):2608-13. doi: 10.1073/pnas.1324240111